The Georgie project sends out periodic reports of our findings. These reports are generally sent to the participants along with detailed information on their dogs. Here we have reproduce the public versions of the report for your reference. If you participated in a specific study and did not receive a report on your specific dog please contact the Georgie Project.
UPDATES
In 1997 we conducted an extensive survey of 360 Portuguese Water Dogs. We were trying to get an idea of which characteristics of the breed were varying. These characterisitcs could then be used for genetic analysis. Read the Survey results for more details.
Genetic
founder analysis of Cardiomyopathy.
Geneitc founder analysis of GM1
Georgie Project Specialty Report 2001
GREAT VIDEO FOOTAGE OF THE GEORGIE PROJECT
The Georgie project has been featured in a Daily Planet video. EXN.ca has the video on their web site at
http://www.exn.ca/Stories/2002/12/05/53.asp
Chase, K., Lawler, D.F., Carrier, D,R. and K.G. Lark (2005) Genetic regulation of osteoarthritis: A QTL regulating cranial and caudal acetabular osteophyte formation in the hip joint of the dog (Canis familiaris). Amer. J. Med. Genet. 135A(3):334-335. http://www3.interscience.wiley.com/cgi-bin/jtoc/33129/ Carrier DR, Chase K, Lark KG. Genetics of canid skeletal variation: size and shape of the pelvis. Genome Res. 2005 Dec;15(12):1825-30. PMID: 16339381 [PubMed - indexed for MEDLINE] Chase K, Carrier DR, Adler FR, Ostrander EA, Lark KG. Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water Dogs. Genome Res. 2005 Dec;15(12):1820-4. PMID: 16339380 [PubMed - indexed for MEDLINE] Lark, K.G., Chase, K., Carrier, D.R. and F.R. Adler (2005) Genetic analysis of the canid skeleton: Analysis of morphological loci (QTLs) in the Portuguese Water Dog population. In: "The Genome of the Domestic Dog" (Cold Spring Harbor Monograph Series 44). pp. 67-80. Editors: E.A. Ostrander, U. Giger, and K. Lindblad-Toh. Cold Spring Harbor Press, Cold Spring Harbor, NY. Trut, L.N., Kharlamova, A.V., Carrier, D.R., Chase, K., Kukekova, A.V., Acland, G.M. and K.G. Lark (2005) Morphology and behavior: Are they coupled at the genome level? In: "The Genome of the Domestic Dog² (Cold Spring Harbor Monograph Series 44). pp. 81-93. Editors: E.A. Ostrander, U. Giger, and K. Lindblad-Toh. Cold Spring Harbor Press, Cold Spring Harbor, NY. Lark KG, Chase K, Sutter NB. Genetic architecture of the dog: sexual size dimorphism and functional morphology. Trends Genet. 2006 Oct;22(10):537-44. Epub 2006 Aug 24 PMID: 16934357 [PubMed - in process]
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Bilaterally asymmetric effects of quantitative trait loci
(QTLs): QTLs that affect laxity in the right versus left
coxofemoral (hip) joints of the dog (Canis familiaris). |
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Chase K, Carrier DR, Adler FR, Jarvik T, Ostrander EA, Lorentzen TD, Lark KG. |
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Genetic basis for systems of skeletal quantitative traits:
principal component analysis of the canid skeleton. |
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Alroy J, Rush JE, Freeman L, Amarendhra Kumar MS, Karuri A, Chase K, Sarkar S. |
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Inherited infantile dilated cardiomyopathy in dogs: genetic,
clinical, biochemical, and morphologic findings. |
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Teaching a new dog old tricks: identifying quantitative trait
loci using lessons from plants. |